Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713400 | 0.90 | LMNA (0.81) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL3872687 | 0.86 | LMNA (0.75) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL12713409 | 0.85 | LMNA (0.73) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL12713395 | 0.81 | LMNA (0.69) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL12713406 | 0.75 | LMNA (0.60) | LMNAALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL12713398 | 0.74 | LMNA (0.59) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL12713418 | 0.74 | LMNA (0.58) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL13024525 | 0.73 | POLB (1.00) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL12713391 | 0.70 | LMNA (0.64) | LMNAALDH1A1RXFP1HPGDKDM4E | |
| SCHEMBL13814576 | 0.69 | ALDH1A1 (0.68) | LMNAALDH1A1RXFP1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657031-B2 | Ant-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2017-05-23 | — | — | US | disclosed |
| US-9657031-B2 | Ant-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2017-05-23 | — | — | US | disclosed |
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2014-11-27 | — | — | US | disclosed |
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2014-11-27 | — | — | US | disclosed |
| US-8809346-B2 | ANT-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2014-08-19 | — | — | US | disclosed |
| US-8809346-B2 | ANT-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2014-08-19 | — | — | US | disclosed |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2011-04-14 | — | — | US | disclosed |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | CXCR3, ACKR3, CCR3 | LMNA 2370/4885ALDH1A1 2899/4885RXFP1 605/4885 |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | CXCR3, ACKR3, CCR3 | LMNA 2515/4885ALDH1A1 2352/4885RXFP1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.