SCHEMBL1271508

SCHEMBL1271508

O=C(O)CC(F)C(F)(F)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
FOLH1 Q04609 2/20 0.34
ACLY P53396 2/20 0.33
GABRR1 P24046 2/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.30
GPR84 Q9NQS5 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25288474 0.79 SLC22A6 (0.33) SLC22A6TDP1SMN1; SMN2FOLH1
SCHEMBL25289696 0.79
SCHEMBL29211171 0.79 SLC22A6 (0.41) SLC22A6TDP1SMN1; SMN2FOLH1ACLY
SCHEMBL1706476 0.76 CHRM1 (0.41) TDP1TSHRGPR84
SCHEMBL28719269 0.75 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2FOLH1GABRR1
SCHEMBL5262338 0.75 TET2 (0.30)
SCHEMBL1704335 0.75 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2FOLH1GABRR1
SCHEMBL1706440 0.75 MAPT (0.31)
Hydrochloric Acid SCHEMBL11748281 0.75 CHRM1 (0.39) TDP1TSHR
Methylene Chloride SCHEMBL244765 0.73 SLC22A6 (0.36) SLC22A6TDP1SMN1; SMN2FOLH1ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170320312-A1 METHOD FOR MANUFACTURING PRINTED MATTER TORAY INDUSTRIES, INC. (JP) 2017-11-09 US disclosed
US-20130052368-A1 METHODS FOR PREPARING THIN FILMS BY ATOMIC LAYER DEPOSITION USING HYDRAZINES SIGMA-ALDRICH CO. LLC (US) 2013-02-28 US disclosed
WO-2012173675-A1 DEPOSITION PROCESSES FOR PHOTOVOLTAICS PRECURSOR ENERGETICS, INC. (US) 2012-12-20 WO disclosed
EP-2462150-A2 POLYMERIC PRECURSORS FOR CAIGS AND AIGS SILVER-CONTAINING PHOTOVOLTAICS Precursor Energetics, Inc. (US) 2012-06-13 EP disclosed
EP-2462151-A2 POLYMERIC PRECURSORS FOR CAIGAS ALUMINUM-CONTAINING PHOTOVOLTAICS Precursor Energetics, Inc. (US) 2012-06-13 EP disclosed
WO-2011115878-A1 METHODS FOR PREPARING THIN FILLMS BY ATOMIC LAYER DEPOSITION USING HYDRAZINES SIGMA-ALDRICH CO. (US) 2011-09-22 WO disclosed
WO-2011084171-A1 MOLECULAR PRECURSORS FOR OPTOELECTRONICS PRECURSOR ENERGETICS, INC. (US) 2011-07-14 WO disclosed
WO-2011017237-A2 POLYMERIC PRECURSORS FOR CAIGS AND AIGS SILVER-CONTAINING PHOTOVOLTAICS PRECURSOR ENERGETICS, INC. (US) 2011-02-10 WO disclosed
WO-2011017238-A2 POLYMERIC PRECURSORS FOR CAIGAS ALUMINUM-CONTAINING PHOTOVOLTAICS PRECURSOR ENERGETICS, INC. (US) 2011-02-10 WO disclosed
US-20080279809-A1 COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES HENKEL AG & CO. KGAA (DE) 2008-11-13 US disclosed
EP-0746563-A1 METHOD FOR THE DEPOSITION OF NICKEL AND/OR NICKEL OXIDE FROM THE GAS PHASE, AND NOVEL NICKEL COMPOUNDS HAVING STABLE VAPORISATION CHARACTERISTICS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1996-12-11 EP disclosed
WO-1995023155-A1 METHOD FOR THE DEPOSITION OF NICKEL AND/OR NICKEL OXIDE FROM THE GAS PHASE, AND NOVEL NICKEL COMPOUNDS HAVING STABLE VAPORISATION CHARACTERISTICS NEDERLANDSE ORGANISATIE VOOR TOEGEPASTNATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1995-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080279809-A1 COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES ZKSCAN2, CAD, ZRANB2 SLC22A6 4579/4885TDP1 3782/4885SMN1; SMN2 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.