SCHEMBL1271509

SCHEMBL1271509

O=C(O)C(F)C(F)C(F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ABCB11 O95342 1/20 0.33
F2 P00734 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2C19 P33261 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN5 P54829 1/20 0.33
PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28427549 0.92 ALDH1A1 (0.44) ALDH1A1LMNATSHRTHRBRECQL
SCHEMBL8395914 0.86 LMNA (0.32) ALDH1A1LMNATSHRTHRBRECQL
SCHEMBL2069150 0.84 ALDH1A1 (0.40) ALDH1A1LMNATSHRTHRBRECQL
SCHEMBL25264603 0.83 ALDH1A1 (0.37) ALDH1A1LMNATSHRTHRBRECQL
SCHEMBL25279866 0.83
SCHEMBL29103987 0.81 ALDH1A1 (0.42) ALDH1A1TSHRTHRBRECQLCYP2C19
SCHEMBL29263773 0.81 ALDH1A1 (0.35) ALDH1A1THRBRECQLCYP2C19
SCHEMBL22029926 0.81 ALDH1A1 (0.35) ALDH1A1THRBRECQLCYP2C19
Fluoride SCHEMBL19466427 0.80 ALDH1A1 (0.38) ALDH1A1LMNATSHRTHRBRECQL
Ammonia Solution, Strong SCHEMBL17652259 0.78 ALDH1A1 (0.33) ALDH1A1THRBRECQLCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170320312-A1 METHOD FOR MANUFACTURING PRINTED MATTER TORAY INDUSTRIES, INC. (JP) 2017-11-09 US disclosed
US-20130052368-A1 METHODS FOR PREPARING THIN FILMS BY ATOMIC LAYER DEPOSITION USING HYDRAZINES SIGMA-ALDRICH CO. LLC (US) 2013-02-28 US disclosed
WO-2012173675-A1 DEPOSITION PROCESSES FOR PHOTOVOLTAICS PRECURSOR ENERGETICS, INC. (US) 2012-12-20 WO disclosed
EP-2462151-A2 POLYMERIC PRECURSORS FOR CAIGAS ALUMINUM-CONTAINING PHOTOVOLTAICS Precursor Energetics, Inc. (US) 2012-06-13 EP disclosed
EP-2462150-A2 POLYMERIC PRECURSORS FOR CAIGS AND AIGS SILVER-CONTAINING PHOTOVOLTAICS Precursor Energetics, Inc. (US) 2012-06-13 EP disclosed
WO-2011115878-A1 METHODS FOR PREPARING THIN FILLMS BY ATOMIC LAYER DEPOSITION USING HYDRAZINES SIGMA-ALDRICH CO. (US) 2011-09-22 WO disclosed
WO-2011084171-A1 MOLECULAR PRECURSORS FOR OPTOELECTRONICS PRECURSOR ENERGETICS, INC. (US) 2011-07-14 WO disclosed
WO-2011017238-A2 POLYMERIC PRECURSORS FOR CAIGAS ALUMINUM-CONTAINING PHOTOVOLTAICS PRECURSOR ENERGETICS, INC. (US) 2011-02-10 WO disclosed
WO-2011017237-A2 POLYMERIC PRECURSORS FOR CAIGS AND AIGS SILVER-CONTAINING PHOTOVOLTAICS PRECURSOR ENERGETICS, INC. (US) 2011-02-10 WO disclosed
US-20080279809-A1 COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES HENKEL AG & CO. KGAA (DE) 2008-11-13 US disclosed
EP-0746563-A1 METHOD FOR THE DEPOSITION OF NICKEL AND/OR NICKEL OXIDE FROM THE GAS PHASE, AND NOVEL NICKEL COMPOUNDS HAVING STABLE VAPORISATION CHARACTERISTICS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1996-12-11 EP disclosed
WO-1995023155-A1 METHOD FOR THE DEPOSITION OF NICKEL AND/OR NICKEL OXIDE FROM THE GAS PHASE, AND NOVEL NICKEL COMPOUNDS HAVING STABLE VAPORISATION CHARACTERISTICS NEDERLANDSE ORGANISATIE VOOR TOEGEPASTNATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1995-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080279809-A1 COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES ZKSCAN2, CAD, ZRANB2 ALDH1A1 3621/4885LMNA 3867/4885TSHR 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.