Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986334 | 0.90 | HPSE (0.52) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL13986332 | 0.90 | L3MBTL3 (0.52) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10191057 | 0.89 | FOLH1 (0.55) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL12640284 | 0.89 | PRSS1 (0.37) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL21008402 | 0.89 | FOLH1 (0.55) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL12715288 | 0.83 | CA12 (0.57) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL5806320 | 0.80 | FOLH1 (0.52) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL13986286 | 0.78 | HPSE (0.57) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL14315660 | 0.78 | FOLH1 (0.55) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10246039 | 0.76 | FOLH1 (0.58) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923582-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-04-12 | — | — | US | disclosed |
| US-7838665-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-11-23 | — | — | US | disclosed |
| US-7667012-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product; N-azidogalactosamine | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-23 | — | — | US | disclosed |
| US-20080214801-A1 | CHEMOSELECTIVE LIGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214801-A1 | CHEMOSELECTIVE LIGATION | PTMS, QPCT, DNPEP | PRSS1 3193/4885PRSS2 3801/4885PRSS3 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.