Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21008402 | 0.99 | FOLH1 (0.55) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL13986332 | 0.95 | L3MBTL3 (0.52) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL13986334 | 0.95 | HPSE (0.52) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL14315660 | 0.90 | FOLH1 (0.55) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL12715293 | 0.89 | PRSS1 (0.48) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL10246039 | 0.88 | FOLH1 (0.58) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL5806320 | 0.86 | FOLH1 (0.52) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL12715288 | 0.80 | CA12 (0.57) | PKMHPSETDP1 | |
| SCHEMBL19326754 | 0.80 | PKM (0.60) | FOLH1HSP90AB1LY6KPRSS1PRSS2 | |
| SCHEMBL13528559 | 0.79 | PKM (0.60) | FOLH1HSP90AB1LY6KPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216871-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | INVITROGEN CORPORATION | 2020-07-09 | — | — | US | disclosed |
| EP-2535423-B1 | Labeling and detection of nucleic acids | LIFE TECHNOLOGIES CORP (US) | 2019-05-15 | — | — | EP | disclosed |
| US-20170362624-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | Life Technologies Corporation | 2017-12-21 | — | — | US | disclosed |
| US-20170362624-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | Life Technologies Corporation | 2017-12-21 | — | — | US | disclosed |
| EP-2623986-B1 | Labeling and detection of post translationally modified proteins | LIFE TECHNOLOGIES CORP (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9645140-B2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-9645140-B2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| EP-2623609-B1 | Labeling and detection of post translationally modified proteins | LIFE TECHNOLOGIES CORP (US) | 2017-01-04 | — | — | EP | disclosed |
| US-9211520-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| EP-2623610-B1 | Labeling and detection of post translationally modified proteins | LIFE TECHNOLOGIES CORP (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2623610-A2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-2623986-A2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-2623609-A2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20120301894-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | Life Technologies Corporation (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120301894-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | Life Technologies Corporation (US) | 2012-11-29 | — | — | US | disclosed |
| US-8114636-B2 | Labeling and detection of nucleic acids | Life Technologies Corporation (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100261181-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | Life Technologies Corporation (US) | 2010-10-14 | — | — | US | disclosed |
| US-20080050731-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | INVITROGEN CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| US-20070249014-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | INVITROGEN CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
| US-20070249014-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | INVITROGEN CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216871-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | PTMS, DNPEP, BTD | FOLH1 610/4885HSP90AB1 1620/4885LY6K 175/4885 |
| US-20070249014-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | PTMS, DNPEP, BTD | FOLH1 610/4885HSP90AB1 1620/4885LY6K 175/4885 |
| US-20170362624-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | PTMS, DNPEP, BTD | FOLH1 610/4885HSP90AB1 1620/4885LY6K 175/4885 |
| US-20100261181-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | RNGTT, ADAR, ALKBH1 | FOLH1 1109/4885HSP90AB1 3267/4885LY6K 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.