Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.67 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desomorphine SCHEMBL678973 | 1.00 | OPRD1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Desomorphine SCHEMBL24969 | 1.00 | OPRD1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Desomorphine SCHEMBL11630127 | 1.00 | OPRD1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Desomorphine SCHEMBL46252 | 1.00 | OPRD1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL15866691 | 0.94 | OPRD1 (0.60) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL16866227 | 0.94 | OPRD1 (0.60) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL11631069 | 0.85 | OPRM1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2 | |
| SCHEMBL21202077 | 0.85 | OPRM1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2 | |
| SCHEMBL21202024 | 0.85 | OPRM1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2 | |
| SCHEMBL11631074 | 0.85 | OPRM1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399161-B1 | SUSTAINED-RELEASE ANALGESIC COMPOUNDS | CONTROL DELIVERY SYSTEMS (US) | 2011-04-20 | — | — | EP | disclosed |