Desomorphine

Desomorphine

SCHEMBL46252

CN1CCC23c4c5ccc(O)c4OC2CCCC3C1C5

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 9/20 0.67
OPRM1 P35372 8/20 0.67
OPRK1 P41145 7/20 0.67
MRGPRX2 Q96LB1 2/20 0.57
SLC22A1 O15245 1/20 0.57
ADRA2A P08913 1/20 0.57
ARRB1 P49407 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desomorphine SCHEMBL678973 1.00 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
Desomorphine SCHEMBL24969 1.00 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
Desomorphine SCHEMBL11630127 1.00 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
Desomorphine SCHEMBL12720171 1.00 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL15866691 0.94 OPRD1 (0.60) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL16866227 0.94 OPRD1 (0.60) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL11631069 0.85 OPRM1 (0.67) OPRD1OPRM1OPRK1MRGPRX2
SCHEMBL21202077 0.85 OPRM1 (0.67) OPRD1OPRM1OPRK1MRGPRX2
SCHEMBL21202024 0.85 OPRM1 (0.67) OPRD1OPRM1OPRK1MRGPRX2
SCHEMBL11631074 0.85 OPRM1 (0.67) OPRD1OPRM1OPRK1MRGPRX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115885037-A Midbrain organoid, high-speed large-scale production method thereof, method for screening neurotoxic substance and method for screening dopaminergic neuron-related disease drug using the same 广东省奥干诺伊德生物科技有限公司 2023-03-31 CN claimed
CN-112402386-B Abuse-preventing opioid oral sustained-release tablet and preparation method thereof 江苏恩华药业股份有限公司 2022-06-28 CN claimed
CN-113840621-A Vaccination and antibody generation platform 德国癌症研究公共权益基金会 2021-12-24 CN claimed
CN-112840018-A Method for inducing differentiation of dopamine neural precursor cells from stem cells S生物医药公司 2021-05-25 CN claimed
CN-112402386-A Abuse-proof opioid oral sustained release tablet and preparation method thereof 江苏恩华药业股份有限公司 2021-02-26 CN claimed
CN-110831575-A Pharmaceutical preparation 卡里亚制药控股有限公司 2020-02-21 CN claimed
CN-102406640-A Analgesic and antiphlogistic medicines and micro-needle transdermal administration method for same SHANGHAI TAIYIN BIOLOG TECHNOLOGY CO LTD 2012-04-11 CN claimed
CN-100409847-C Transdermal delivery system for alkaloids of aconitum species XEL HERBACEUTICALS (US) 2008-08-13 CN claimed
CN-1450883-A Transdermal delivery system for alkaloids of aconitum species XEL HERBACEUTICALS (US) 2003-10-22 CN claimed
CN-1069544-C Thebaica giving-up vaccinum for man KUNMING BIOLOG TECH ENGINEERIN (CN) 2001-08-15 CN claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
CN-1196955-A Thebaica giving-up vaccinum for man KUNMING BIOLOG TECH ENGINEERIN (CN) 1998-10-28 CN claimed
CN-119524126-A Pharmaceutical resinated compositions and methods of making and using the same 罗兹制药公司 2025-02-28 CN disclosed
WO-2024194018-A1 METHOD FOR PRODUCING CORYTUBERINE AND SALUTARIDINE Universität Graz (AT) 2024-09-26 WO disclosed
EP-4431612-A1 PROCESS FOR THE PREPARATION OF CORORYLOURIN AND SALUTARIDINE Universität Graz (AT) 2024-09-18 EP disclosed
CN-118234483-A Compositions and methods for infusing a drug into the bladder 特瑞纲制药有限公司 2024-06-21 CN disclosed
CN-1450883-A Transdermal delivery system for alkaloids of aconitum species XEL HERBACEUTICALS (US) 2003-10-22 CN disclosed
CN-1069544-C Thebaica giving-up vaccinum for man KUNMING BIOLOG TECH ENGINEERIN (CN) 2001-08-15 CN disclosed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN disclosed
CN-1196955-A Thebaica giving-up vaccinum for man KUNMING BIOLOG TECH ENGINEERIN (CN) 1998-10-28 CN disclosed