Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1582681 | 0.99 | ADRA1D (0.41) | HTR1AADRA1DDRD2DRD4DRD3 | |
| SCHEMBL1583166 | 0.92 | DRD2 (0.40) | HTR1AADRA1DDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL1582377 | 0.91 | ADRA1D (0.40) | HTR1AADRA1DDRD2DRD4DRD3 | |
| SCHEMBL1582770 | 0.89 | KCNH2 (0.40) | HTR1AADRA1DDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL1582892 | 0.88 | ADRA1D (0.40) | HTR1AADRA1DDRD2DRD4DRD3 | |
| SCHEMBL1582888 | 0.85 | DRD2 (0.59) | HTR1ADRD2DRD4DRD3CLK2 | |
| Hydrochloric Acid SCHEMBL1582510 | 0.84 | DRD2 (0.58) | HTR1AADRA1DDRD2DRD4DRD3 | |
| SCHEMBL1583360 | 0.82 | GLRA3 (0.47) | HTR1AADRA1DNMT2NMT1 | |
| SCHEMBL1582816 | 0.82 | DRD2 (0.39) | HTR1AADRA1DDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL1582650 | 0.82 | GLRA3 (0.46) | HTR1AADRA1DNMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | disclosed |