Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1582377 | 0.99 | ADRA1D (0.40) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL12720973 | 0.92 | HTR1A (0.39) | DRD2DRD4DRD3HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL1582681 | 0.91 | ADRA1D (0.41) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL1582770 | 0.89 | KCNH2 (0.40) | DRD2DRD4DRD3HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL1582892 | 0.88 | ADRA1D (0.40) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL1582251 | 0.84 | DRD2 (0.61) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL7394277 | 0.83 | HTR1B (0.49) | DRD2DRD4DRD3HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL1582642 | 0.83 | DRD2 (0.60) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL1583365 | 0.82 | GLRA3 (0.51) | DRD2DRD4DRD3HTR1ANMT2 | |
| Hydrochloric Acid SCHEMBL1582269 | 0.81 | GLRA3 (0.50) | DRD2DRD4DRD3HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | disclosed |