SCHEMBL12721997

SCHEMBL12721997

Fc1ccc(-n2c3ccccc3c3cc(N(c4ccc(-c5ccccc5)cc4)c4ccc5c(c4)c4cc([Si](c6ccccc6)(c6ccccc6)c6ccccc6)ccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NR3C1 P04150 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.34
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
MAPK14 Q16539 1/20 0.32
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
KMT2A Q03164 2/20 0.32
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
CACNG2 Q9Y698 1/20 0.32
PTGER4 P35408 1/20 0.31
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12722019 1.00 KDM4E (0.38) KDM4EATML3MBTL1NR3C1PTGDR2
SCHEMBL12722045 0.99 NR3C1 (0.37) KDM4EATML3MBTL1NR3C1PTGDR2
SCHEMBL12721671 0.97 NR3C1 (0.39) KDM4EATML3MBTL1NR3C1PTGDR2
SCHEMBL13249741 0.96 NR3C1 (0.39) NR3C1PTGDR2JAK2JAK3KMT2A
SCHEMBL12721751 0.96 NR3C1 (0.37) KDM4EATML3MBTL1NR3C1PTGDR2
SCHEMBL12231661 0.96 KDM4E (0.41) KDM4EATML3MBTL1NR3C1PTGDR2
SCHEMBL12721955 0.96 NR3C1 (0.39) NR3C1PTGDR2JAK2JAK3KMT2A
SCHEMBL13249714 0.96 NR3C1 (0.39) NR3C1PTGDR2JAK2JAK3KMT2A
SCHEMBL12722006 0.96 KDM4E (0.41) KDM4EATML3MBTL1NR3C1PTGDR2
SCHEMBL12721654 0.96 KDM4E (0.41) KDM4EATML3MBTL1NR3C1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7927719-B2 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-04-19 US disclosed
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND ICMT, SLC43A1, SLC7A5 KDM4E 2673/4885ATM 4190/4885L3MBTL1 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.