Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993634 | 0.91 | MAPT (0.42) | THRBMAPTMAPK1TSHRLMNA | |
| SCHEMBL10564103 | 0.87 | ALDH1A1 (0.44) | THRBMAPTMAPK1LMNA | |
| SCHEMBL27560768 | 0.86 | MAPT (0.34) | MAPTMAPK1LMNA | |
| SCHEMBL194450 | 0.82 | GPR84 (0.38) | MAPTMAPK1LMNA | |
| SCHEMBL15327774 | 0.81 | TSHR (0.37) | THRBTSHR | |
| SCHEMBL10557312 | 0.80 | MAPT (0.61) | MAPTMAPK1LMNA | |
| SCHEMBL9394352 | 0.80 | MAPT (0.61) | MAPTMAPK1LMNA | |
| SCHEMBL6350299 | 0.79 | MAPT (0.41) | MAPTMAPK1TSHRLMNA | |
| SCHEMBL1271507 | 0.79 | MAPT (0.39) | MAPTMAPK1TSHRLMNA | |
| SCHEMBL3068283 | 0.79 | THRB (0.41) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011018161-A1 | COMPOUNDS FOR QUENCHING REACTIVE METAL CATALYTIC SPECIES REMAINED IN POLYESTER POLYOL RESINS, QUENCHING PROCESS AND ITS APPLICATION IN POLYURETHANE PRODUCTION THEREIN | BAYER MATERIALSCIENCE AG (DE) | 2011-02-17 | — | — | WO | disclosed |