Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12722974 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP2C19CA1KISS1R | |
| SCHEMBL5107560 | 0.81 | THRB (0.39) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL391722 | 0.81 | THRB (0.39) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL10740374 | 0.81 | GPR84 (0.39) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL9566376 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL110123 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL12894212 | 0.76 | KDM4E (0.39) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL12384861 | 0.76 | KDM4E (0.39) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL8729467 | 0.75 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL5665861 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM4EKDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932403-B2 | Process for preparing pyrrole derivatives and intermediates | RATIOPHARM GMBH (DE) | 2011-04-26 | — | — | US | disclosed |