Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CD38 | P28907 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 2/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505239 | 0.88 | ALDH1A1 (0.68) | MEN1KMT2ANPC1KDM4ERAB9A | |
| SCHEMBL12725538 | 0.88 | HIF1A (0.53) | MEN1KMT2ACD38AURKARPS6KB1 | |
| SCHEMBL28658000 | 0.87 | AURKA (0.65) | MEN1KMT2APKMCD38AURKA | |
| SCHEMBL8366816 | 0.87 | HDAC1 (0.58) | MEN1KMT2APKMCD38AURKA | |
| SCHEMBL9741286 | 0.86 | NPC1 (0.53) | MEN1KMT2ACD38AURKARPS6KB1 | |
| SCHEMBL30311719 | 0.85 | RAB9A (0.65) | MEN1KMT2AAURKARPS6KB1NPC1 | |
| SCHEMBL28642513 | 0.85 | RAB9A (0.65) | MEN1KMT2AAURKARPS6KB1NPC1 | |
| SCHEMBL28658005 | 0.83 | RAB9A (0.59) | MEN1KMT2ACD38NPC1KDM4E | |
| SCHEMBL7760016 | 0.83 | HPGD (0.53) | MEN1KMT2ACD38NPC1KDM4E | |
| SCHEMBL30311518 | 0.82 | HSD17B10 (0.63) | MEN1KMT2ACD38AURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098483-A1 | Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098483-A1 | Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof | PAH, NAT1, NNT | MEN1 124/4885KMT2A 2793/4885PKM 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.