⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531469 | 0.78 | POLB (0.34) | — | |
| SCHEMBL12729559 | 0.77 | DNMT1 (0.37) | — | |
| SCHEMBL17833865 | 0.75 | POLB (0.35) | — | |
| SCHEMBL12729592 | 0.70 | HDAC1 (0.37) | — | |
| SCHEMBL12729560 | 0.70 | P2RY2 (0.41) | — | |
| SCHEMBL12729571 | 0.70 | ADORA3 (0.33) | — | |
| SCHEMBL12729601 | 0.70 | KDM4E (0.39) | — | |
| SCHEMBL12531609 | 0.65 | LMNA (0.40) | — | |
| SCHEMBL16503451 | 0.64 | DUT (0.36) | — | |
| SCHEMBL1592652 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |
| US-9163053-B2 | Nucleotide analogs | FLUIDIGM CORPORATION (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163053-B2 | Nucleotide analogs | FLUIDIGM CORPORATION (US) | 2015-10-20 | — | — | US | disclosed |
| US-20110081647-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION (US) | 2011-04-07 | — | — | US | disclosed |