SCHEMBL12733130

SCHEMBL12733130

O=C(c1cc(O)c(C(=O)C2CCc3ccccc32)cc1O)C1CCc2ccccc21

nearest known ligand 0.77

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 12/20 0.77
PPIA P62937 3/20 0.57
PPID Q08752 2/20 0.57
PPIB P23284 2/20 0.57
PPIL1 Q9Y3C6 1/20 0.49
TAS1R3 Q7RTX0 3/20 0.44
TAS1R1 Q7RTX1 3/20 0.44
TAS1R2 Q8TE23 3/20 0.44
KCNQ2 O43526 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16016168 0.86 PIN1 (0.65) PIN1PPIAPPIDPPIBPPIL1
SCHEMBL28002431 0.80 PIN1 (0.66) PIN1PPIAPPIDPPIBKCNQ2
SCHEMBL28002344 0.79 PIN1 (0.70) PIN1PPIAPPIDPPIBTAS1R3
SCHEMBL30799263 0.79 PIN1 (0.70) PIN1PPIAPPIDPPIBPPIL1
SCHEMBL4830828 0.77 PIN1 (0.62) PIN1KCNQ2
SCHEMBL30799232 0.76 PIN1 (0.57) PIN1PPIAPPIDPPIBPPIL1
SCHEMBL27914923 0.76 PIN1 (0.57) PIN1PPIAPPIDPPIBPPIL1
SCHEMBL12431131 0.75 PIN1 (0.60) PIN1KCNQ2
SCHEMBL2790690 0.75 PIN1 (0.60) PIN1KCNQ2
SCHEMBL907688 0.75 PIN1 (0.60) PIN1KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
EP-1818725-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Hodogaya Chemical Co., Ltd. (JP) 2007-08-15 EP disclosed