Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.62 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907688 | 0.86 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL12431131 | 0.86 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL1400973 | 0.86 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL1567245 | 0.86 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL2790690 | 0.86 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL5609883 | 0.84 | PIN1 (0.58) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL643577 | 0.84 | PIN1 (0.58) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL8848989 | 0.84 | PIN1 (0.58) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| Hydrochloric Acid SCHEMBL7213722 | 0.84 | PIN1 (0.58) | PIN1KCNQ2IDO1PDPK1TSHR | |
| SCHEMBL2475968 | 0.84 | PIN1 (0.58) | PIN1KCNQ2IDO1PDPK1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110330442-A | A kind of 2,2- bis- replaces the synthetic method of indane ketone compound | 常州大学 | 2019-10-15 | — | — | CN | claimed |
| CN-107880062-A | A kind of organic photovoltaic donor small molecule material and its preparation method and application | 苏州大学 | 2018-04-06 | — | — | CN | claimed |
| CN-105348062-B | Preparation method of 3-aryl-1-indanone derivate | 清华大学 | 2017-03-22 | — | — | CN | claimed |
| CN-103906733-A | TRMP8 antagonists and their use in treatments | AMGEN INC | 2014-07-02 | — | — | CN | claimed |
| CN-115894141-A | Synthesis method of acylindene derivatives | 贺州学院 | 2023-04-04 | — | — | CN | disclosed |
| CN-104662155-B | Plants with enhanced tolerance to herbicides | 巴斯夫农业公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110330442-A | A kind of 2,2- bis- replaces the synthetic method of indane ketone compound | 常州大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-110330442-A | A kind of 2,2- bis- replaces the synthetic method of indane ketone compound | 常州大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-110330442-A | A kind of 2,2- bis- replaces the synthetic method of indane ketone compound | 常州大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-105712993-B | Compound for organic electro-optic device and organic electro-optic device and imaging sensor including it | 三星电子株式会社 | 2019-10-01 | — | — | CN | disclosed |
| CN-107207999-B | Lightening compositions | 荷兰联合利华有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-106661504-B | Lightening compositions | 荷兰联合利华有限公司 | 2019-07-12 | — | — | CN | disclosed |
| EP-0785989-A4 | MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0785786-A4 | MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0785989-A1 | MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS | Merck & Co., Inc. (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0785786-A1 | MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS | Merck & Co., Inc. (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996012790-A1 | MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | disclosed |
| WO-1996012492-A1 | MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | disclosed |
| CN-1029960-C | Process for preparing chromanol derivatives having neuroprotective effect | PFIZER (US) | 1995-10-11 | — | — | CN | disclosed |
| CN-1053923-A | 3-piperidino-(1-position only)-4-hydroxy benzo dichloro-pyran derivative with neuroprotective | PFIZER (US) | 1991-08-21 | — | — | CN | disclosed |