Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733169 | 0.87 | CA2 (0.44) | TSHRCYP1A2CYP2C9CYP2C19ALOX5 | |
| SCHEMBL11337534 | 0.86 | CYP1A2 (0.39) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9318674 | 0.85 | CYP1A2 (0.38) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12733173 | 0.84 | CYP1A2 (0.32) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12733165 | 0.84 | ESR1 (0.36) | CYP3A4ALDH1A1 | |
| SCHEMBL12733178 | 0.83 | — | — | |
| SCHEMBL14429576 | 0.72 | IDO1 (0.37) | CYP1A2CYP3A4EGFRMAPK1CA2 | |
| SCHEMBL18593382 | 0.72 | TSHR (0.44) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18593380 | 0.70 | CYP1A2 (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9002281 | 0.70 | TSHR (0.46) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919219-B2 | Electrophotographic photosensitive body | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-20080044750-A1 | Electrophotographic Photosensitive Body | HODOGAYA CHEMICAL CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |