Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733166 | 0.85 | TSHR (0.39) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL11337534 | 0.84 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL12733169 | 0.72 | CA2 (0.44) | CYP1A2CYP2C9TSHRCYP2C19ALOX5 | |
| SCHEMBL12733173 | 0.69 | CYP1A2 (0.32) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL12733165 | 0.69 | ESR1 (0.36) | CYP3A4 | |
| SCHEMBL12733178 | 0.68 | — | — | |
| SCHEMBL9002281 | 0.68 | TSHR (0.46) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL18593382 | 0.67 | TSHR (0.44) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29350736 | 0.66 | NPC1 (0.49) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29708 | 0.66 | NPC1 (0.49) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576527-A1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | Ciba SC Holding AG (CH) | 1994-01-05 | — | — | EP | claimed |
| WO-1992014718-A1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-09-03 | — | — | WO | claimed |