Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17411218 | 0.83 | NPSR1 (0.43) | METAP2EGLN1NISCHNPC1RAB9A | |
| SCHEMBL12514799 | 0.81 | NPC1 (0.50) | METAP2TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12514795 | 0.81 | METAP2 (0.43) | METAP2UCHL1TP53EGLN1NISCH | |
| SCHEMBL9613254 | 0.81 | MAPT (0.47) | METAP2TP53EGLN1NISCHNPC1 | |
| SCHEMBL16542181 | 0.81 | IDO1 (0.34) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL16542138 | 0.80 | UCHL1 (0.34) | UCHL1TP53EGLN1NPC1RAB9A | |
| SCHEMBL12092479 | 0.80 | RAB9A (0.54) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2776957 | 0.78 | TP53 (0.56) | METAP2UCHL1TP53NISCHSMN1; SMN2 | |
| SCHEMBL1702558 | 0.78 | TP53 (0.56) | METAP2UCHL1TP53NISCHSMN1; SMN2 | |
| SCHEMBL10272489 | 0.78 | MCHR1 (0.47) | NPC1RAB9ASMN1; SMN2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974693-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2015-03-10 | — | — | US | disclosed |
| US-8956550-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-17 | — | — | US | disclosed |
| US-8956549-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-17 | — | — | US | disclosed |
| US-8551358-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2013-10-08 | — | — | US | disclosed |
| US-20110095229-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-04-28 | — | — | US | disclosed |