SCHEMBL1273561

SCHEMBL1273561

CCCC[C@H](C)C[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CC(=O)C1CCC(C(=O)O)CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGIR P43119 9/20 0.58
▸ TSHR P16473 3/20 0.50
▸ PTGER4 P35408 3/20 0.50
▸ PTGER2 P43116 3/20 0.50
▸ HPGD P15428 2/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ ABCC3 O15438 1/20 0.50
▸ ABCC4 O15439 1/20 0.50
▸ RARB P10826 1/20 0.50
▸ RARG P13631 1/20 0.50
▸ DRD1 P21728 1/20 0.50
▸ NR4A2 P43354 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ NR1I2 O75469 1/20 0.48
▸ ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4915632 1.00 PTGIR (0.58) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL9943423 1.00 PTGIR (0.58) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL4915651 1.00 PTGIR (0.58) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL24244641 0.87 PTGIR (0.65) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL958202 0.83 PTGIR (0.68) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL958200 0.83 PTGIR (0.68) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL958197 0.83 PTGIR (0.68) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL10879707 0.82 PTGIR (0.58) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL22489095 0.81 PTGIR (0.67) PTGIRTSHRPTGER4PTGER2HPGD
SCHEMBL960741 0.80 PTGIR (0.78) PTGIRTSHRPTGER4PTGER2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305304-A1 IMMUNOPOTENTIATING AGENT COMPRISING EP1 AGONIST National University Corporation Hamamatsu University School of Medicine (JP) 2011-04-06 — — EP claimed
US-20110038884-A1 IMMUNOPOTENTIATING AGENT COMPRISING EP1 AGONIST NATIONAL UNIVERSITY CO., HAMAMATSU UNIVER. SCHOOL OF MEDICINE (JP) 2011-02-17 — — US claimed
US-20260144801-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-28 — — US disclosed
US-20260022403-A1 VCN ENHANCER COMPOSITIONS AND METHODS OF USING THE SAME BLUEBIRD BIO INC (US) 2026-01-22 — — US disclosed
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 — — US disclosed
EP-4538365-A2 COMPOSITIONS AND METHODS FOR MUSCLE REGENERATION USING PROSTAGLANDIN E2 The Board Of Trustees Of The Leland Stanford Junior University (US) 2025-04-16 — — EP disclosed
US-20250090549-A1 COMPOSITIONS AND METHODS FOR MUSCLE REGENERATION USING PROSTAGLANDIN E2 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-03-20 — — US disclosed
US-12234476-B2 VCN enhancer compositions and methods of using the same BLUEBIRD BIO, INC. (US) 2025-02-25 — — US disclosed
US-20250041211-A1 OPHTHALMIC PREPARATION AND APPLICATION THEREOF IN TREATMENT OF PRESBYOPIA Eye Hospital, Wenzhou Medical University (CN) 2025-02-06 — — US disclosed
US-20240423970-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-12-26 — — US disclosed
US-20240415849-A1 COMPOSITIONS AND METHODS FOR MUSCLE REGENERATION USING PROSTAGLANDIN E2 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-12-19 — — US disclosed
US-8436026-B2 Treating lung diseases selected from acute pneumonia, pulmonary fibrosis, pulmonary hypertension, chronic obstructive pulmonary disease (COPD), and asthma by administering (E)-[5-[2-[1-phenyl-1-(3-pyridyl)methylideneaminoxy]ethyl]-7,8-dihydronaphthalen-1-yloxy]acetic acid or a salt thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2013-05-07 — — US disclosed
EP-1563846-B1 ENDOGENOUS REPAIR FACTOR PRODUCTION PROMOTERS ONO PHARMACEUTICAL CO (JP) 2012-08-29 — — EP disclosed
EP-2305304-A1 IMMUNOPOTENTIATING AGENT COMPRISING EP1 AGONIST National University Corporation Hamamatsu University School of Medicine (JP) 2011-04-06 — — EP disclosed
US-20110038884-A1 IMMUNOPOTENTIATING AGENT COMPRISING EP1 AGONIST NATIONAL UNIVERSITY CO., HAMAMATSU UNIVER. SCHOOL OF MEDICINE (JP) 2011-02-17 — — US disclosed
US-7547715-B2 Endogenous repair factor production accelerator ONO PHARMACEUTICAL CO., LTD. (JP) 2009-06-16 — — US disclosed
US-20080312326-A1 Method for the Prevention and/or Treatment of Neurodegenerative Diseases Characterized by Administering and Ep1 Receptor Antagonist THE JOHN HOPKINS UNIVERSITY (US) 2008-12-18 — — US disclosed
US-20080299089-A1 ENDOGENEOUS REPAIR FACTOR PRODUCTION PROMOTERS ONO PHARMACEUTICAL CO., LTD. (JP) 2008-12-04 — — US disclosed
US-20060069018-A1 Endogenous repair factor production promoters ONO PHARMACEUTICAL CO., LTD. (JP) 2006-03-30 — — US disclosed
EP-1563846-A1 ENDOGENOUS REPAIR FACTOR PRODUCTION PROMOTERS ONO PHARMACEUTICAL CO., LTD. (JP) 2005-08-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022403-A1 VCN ENHANCER COMPOSITIONS AND METHODS OF USING THE SAME PTGES2, POLN, HPGDS PTGIR 39/4885TSHR 4552/4885PTGER4 18/4885
US-20080312326-A1 Method for the Prevention and/or Treatment of Neurodegenerative Diseases Characterized by Administering and Ep1 Receptor Antagonist PTGER1, PSEN1, EPN1 PTGIR 27/4885TSHR 784/4885PTGER4 41/4885
US-20080299089-A1 ENDOGENEOUS REPAIR FACTOR PRODUCTION PROMOTERS PTGER4, PTGIR, PTGER1 PTGIR 2/4885TSHR 2465/4885PTGER4 1/4885
US-20110038884-A1 IMMUNOPOTENTIATING AGENT COMPRISING EP1 AGONIST PTGER1, CD69, CD4 PTGIR 28/4885TSHR 1864/4885PTGER4 9/4885
US-20060069018-A1 Endogenous repair factor production promoters PTGIR, PTGER4, PTGER1 PTGIR 1/4885TSHR 1968/4885PTGER4 2/4885
US-20260144801-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS CPT1B, HPGD, PTGES PTGIR 42/4885TSHR 2274/4885PTGER4 136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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