SCHEMBL12736627

SCHEMBL12736627

CCN1C(=O)c2ccc(OCOc3ccc4c(c3)C(=O)N(C)C4=O)cc2C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
ALDH1A1 P00352 8/20 0.46
APAF1 O14727 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
KDM4E B2RXH2 3/20 0.46
HTT P42858 1/20 0.46
HPGD P15428 4/20 0.45
MAPK1 P28482 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPT P10636 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
APP P05067 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
F2 P00734 1/20 0.42
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
TPSAB1 Q15661 1/20 0.42
TPSD1 Q9BZJ3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26216147 0.91 APP (0.51) ALDH1A1APAF1MEN1KMT2AKDM4E
SCHEMBL19499368 0.88 ALDH1A1 (0.59) POLBALDH1A1APAF1MEN1KMT2A
SCHEMBL13928043 0.86 ALDH1A1 (0.57) POLBALDH1A1APAF1MEN1KMT2A
SCHEMBL26216143 0.82 ALDH1A1 (0.55) ALDH1A1APAF1MEN1KMT2AKDM4E
SCHEMBL13928044 0.80 ALDH1A1 (0.51) POLBALDH1A1APAF1MEN1KMT2A
SCHEMBL18905640 0.79 KDM4E (0.59) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL18053350 0.78 TDP1 (0.45) ALDH1A1MEN1KMT2AKDM4EHTT
SCHEMBL84311 0.78 ALDH1A1 (0.49) POLBALDH1A1APAF1MEN1KMT2A
SCHEMBL10000446 0.76 POLB (0.51) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL10046075 0.76 POLB (0.59) POLBALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180009967-A1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED FROM SAME TEIJIN LIMITED (JP) 2018-01-11 US disclosed
US-20130281585-A1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2013-10-24 US disclosed
US-20130030095-A1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2013-01-31 US disclosed
US-20110092623-A1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN CHEMICALS, LTD. (JP) 2011-04-21 US disclosed
US-7786197-B2 Flame retardant resin composition and molded articles thereof TEIJIN CHEMICALS, LTD. (JP) 2010-08-31 US disclosed
US-20090231518-A1 OPTICAL FILM, POLARIZATION PLATE AND LIQUID CRYSTAL DISPALY JSR CORPORATION (JP) 2009-09-17 US disclosed