Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985156 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRGRIK1HSD17B10TDP1 | |
| SCHEMBL1824383 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRGRIK1HSD17B10TDP1 | |
| SCHEMBL7781249 | 0.83 | GRIK1 (0.50) | GRIK1GRIA4GRIK3GRIK5 | |
| SCHEMBL29808913 | 0.82 | ALOX15 (0.33) | GRIK1GRIA4GRIK3GRIK5 | |
| Acetic Acid SCHEMBL27618718 | 0.81 | GRIK1 (0.48) | GRIK1GRIA4GRIK3GRIK5 | |
| SCHEMBL27464717 | 0.77 | TSHR (0.41) | ALDH1A1TSHRGRIK1HSD17B10TDP1 | |
| SCHEMBL5813287 | 0.77 | TSHR (0.41) | ALDH1A1TSHRGRIK1HSD17B10TDP1 | |
| SCHEMBL2855141 | 0.77 | TSHR (0.41) | ALDH1A1TSHRGRIK1HSD17B10TDP1 | |
| SCHEMBL16838812 | 0.77 | TSHR (0.42) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL29115441 | 0.77 | TSHR (0.42) | ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9396921-B2 | Method and apparatus for pyrolysis-induced cleavage in peptides and proteins | WYOMING RESEARCH PRODUCTS CENTER (US) | 2016-07-19 | — | — | US | disclosed |
| US-20140284466-A1 | Method and Apparatus for Pyrolysis-induced Cleavage in Peptides and Proteins | THE UNIVERSITY OF WYOMING (US) | 2014-09-25 | — | — | US | disclosed |
| US-8637325-B2 | Method and apparatus for pyrolysis-induced cleavage in peptides and proteins | UNIVERSITY OF WYOMING (US) | 2014-01-28 | — | — | US | disclosed |
| US-20110084203-A1 | METHOD AND APPARATUS FOR PYROLYSIS-INDUCED CLEAVAGE IN PEPTIDES AND PROTEINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110084203-A1 | METHOD AND APPARATUS FOR PYROLYSIS-INDUCED CLEAVAGE IN PEPTIDES AND PROTEINS | DNPEP, PGA5, PEPD | ALDH1A1 4868/4885TSHR 3641/4885GRIK1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.