Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609791 | 0.81 | ENPP2 (0.36) | ROCK2PRKACARPS6KB1IRAK1PRKX | |
| SCHEMBL12738166 | 0.79 | PDE10A (0.35) | ADORA3PDE10A | |
| SCHEMBL1610254 | 0.72 | PDE10A (0.43) | PDE4BPDE4DKDM4EMEN1MAPT | |
| SCHEMBL1608814 | 0.72 | PDE10A (0.43) | PDE4BPDE4DKDM4EMEN1MAPT | |
| SCHEMBL12738438 | 0.71 | PDE10A (0.38) | PDE4BPDE4DMEN1KMT2APDE10A | |
| SCHEMBL12738552 | 0.70 | PDE10A (0.46) | PDE4BPDE4DPDE10A | |
| SCHEMBL12737587 | 0.70 | PDE10A (0.50) | KDM4EMEN1MAPTKMT2APDE10A | |
| SCHEMBL13769059 | 0.70 | PDE10A (0.34) | PDE10A | |
| SCHEMBL12738494 | 0.68 | PDE10A (0.43) | PDE4BPDE4DPDE10A | |
| SCHEMBL11918081 | 0.67 | PDE10A (0.34) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |