Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208033 | 0.74 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL6987050 | 0.73 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL27175668 | 0.73 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL5020551 | 0.72 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL4686390 | 0.72 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL31403216 | 0.71 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8902135 | 0.69 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL422519 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL28273654 | 0.69 | KMT2A (0.62) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL12744426 | 0.69 | ALOX15 (0.36) | ALDH1A1SMN1; SMN2KMT2ALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910611-B2 | Therapeutic agent for restenosis | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100029625-A1 | Therapeutic Agent for Restenosis | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029625-A1 | Therapeutic Agent for Restenosis | NR1H2, NR1H3, LDLR | ALDH1A1 1876/4885SMN1; SMN2 4151/4885KMT2A 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.