Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12745002 | 0.82 | BAZ2B (0.37) | BAZ2BHTR6 | |
| SCHEMBL12826866 | 0.79 | NR1H2 (0.40) | CHRNA7 | |
| SCHEMBL357627 | 0.69 | BAZ2B (0.63) | BAZ2B | |
| SCHEMBL17522579 | 0.69 | BAZ2B (0.40) | BAZ2BCHRNA7 | |
| SCHEMBL12011418 | 0.69 | MEN1 (0.42) | BAZ2B | |
| SCHEMBL1461689 | 0.68 | ALDH1A1 (0.41) | BAZ2B | |
| SCHEMBL12011404 | 0.67 | BAZ2B (0.39) | BAZ2BCHRNA7 | |
| SCHEMBL16468536 | 0.67 | BAZ2B (0.39) | BAZ2BCHRNA7 | |
| SCHEMBL12011405 | 0.67 | BAZ2B (0.39) | BAZ2B | |
| SCHEMBL13557434 | 0.66 | KDM4E (0.55) | BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071289-A1 | AMINOPYRAZOLE AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071289-A1 | AMINOPYRAZOLE AMIDE DERIVATIVE | ARGLU1, ARG1, CNKSR1 | BAZ2B 254/4885HTR6 4232/4885CHRNA7 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.