Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 2/20 | 0.34 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.33 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12300354 | 0.93 | CA1 (0.42) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150462 | 0.86 | CA1 (0.33) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12746699 | 0.85 | LMNA (0.44) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL14071885 | 0.82 | CA1 (0.36) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150509 | 0.82 | POLB (0.44) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL13530678 | 0.82 | POLB (0.44) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150506 | 0.82 | KMT2A (0.37) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL16349579 | 0.80 | KMT2A (0.38) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150465 | 0.78 | PTPN1 (0.41) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL13633941 | 0.78 | PTPN1 (0.41) | CA1CA2CA9P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139604-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150025039-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. | 2015-01-22 | — | — | US | disclosed |
| US-8871785-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20110071101-A1 | Nucleoside Phosphonate Analogs | BOOJAMRA CONSTANTINE G | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025039-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | TYMP, ITPA, PNP | CA1 4501/4885CA2 3997/4885CA9 3440/4885 |
| US-20110071101-A1 | Nucleoside Phosphonate Analogs | TYMP, PNP, NUDT1 | CA1 3855/4885CA2 3759/4885CA9 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.