Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.32 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.32 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12150462 | 0.93 | CA1 (0.33) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12300354 | 0.85 | CA1 (0.42) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL14010400 | 0.85 | LMNA (0.39) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12746702 | 0.82 | CA1 (0.37) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150506 | 0.82 | KMT2A (0.37) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL16349579 | 0.82 | KMT2A (0.38) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150509 | 0.80 | POLB (0.44) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL13530678 | 0.80 | POLB (0.44) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL12150465 | 0.80 | PTPN1 (0.41) | CA1CA2CA9P2RX3P2RX4 | |
| SCHEMBL13633941 | 0.80 | PTPN1 (0.41) | CA1CA2CA9P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429565-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-09-30 | — | — | US | disclosed |