SCHEMBL12750132

SCHEMBL12750132

C=CCO[C@@H]1OC(COCc2ccccc2)[C@@H](O)[C@H](OC(C)C(=O)OCC)C1NC(=O)OCC(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TACR2 P21452 2/20 0.36
▸ SSTR4 P31391 5/20 0.35
▸ MCHR1 Q99705 3/20 0.34
▸ SSTR3 P32745 6/20 0.33
▸ SSTR5 P35346 6/20 0.33
▸ SSTR2 P30874 4/20 0.33
▸ SSTR1 P30872 2/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ CDC25B P30305 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ NT5E P21589 1/20 0.32
▸ LGALS8 O00214 1/20 0.32
▸ TACR1 P25103 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2797350 0.89 SSTR4 (0.42) TACR2SSTR4MCHR1SSTR3SSTR5
SCHEMBL2797352 0.89 SSTR4 (0.42) TACR2SSTR4MCHR1SSTR3SSTR5
SCHEMBL25414267 0.81 MCHR1 (0.39) SSTR4MCHR1SSTR3SSTR5SSTR2
SCHEMBL25412293 0.81 SLC6A2 (0.43) SSTR4MCHR1SSTR3SSTR5SSTR2
SCHEMBL25412287 0.81 SLC6A2 (0.43) SSTR4MCHR1SSTR3SSTR5SSTR2
SCHEMBL2313867 0.80 TLR4 (0.39) MCHR1LGALS8TACR1
SCHEMBL28539502 0.80 SSTR4 (0.42) TACR2SSTR4MCHR1SSTR3SSTR5
SCHEMBL2314211 0.79 TLR4 (0.44) MCHR1PTPN1
SCHEMBL2796378 0.78 NT5E (0.39) TACR2PTPN1CDC25BNT5ELMNA
SCHEMBL2796377 0.78 NT5E (0.39) TACR2PTPN1CDC25BNT5ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915383-B2 Method of separating a peptidoglycan recognition protein from a hemolymph Tenebrio molitor larvae YUHAN CORPORATION (KR) 2011-03-29 — — US disclosed
US-20080312408-A1 Method of Separating a Peptidoglycan Recognition Protein From a Hemolymph Tenebrio Molitor Larvae YUHAN CORPORATION (KR) 2008-12-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312408-A1 Method of Separating a Peptidoglycan Recognition Protein From a Hemolymph Tenebrio Molitor Larvae LRBA, CUTA, TLL1 TACR2 2530/4885SSTR4 2284/4885MCHR1 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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