SCHEMBL127545

SCHEMBL127545

Nc1ccc(C(=O)c2cccc(N)c2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.81
NPC1 O15118 1/20 0.68
MITF O75030 1/20 0.68
LMNA P02545 1/20 0.68
POLB P06746 1/20 0.68
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
CA9 Q16790 2/20 0.63
ATM Q13315 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NOX1 Q9Y5S8 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HSD17B10 Q99714 1/20 0.49
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5832368 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL17744847 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29037240 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL5114913 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL23162465 0.98 PBRM1 (0.78) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL10904319 0.98 PBRM1 (0.78) PBRM1NPC1MITFLMNAPOLB
SCHEMBL17744842 0.98 PBRM1 (0.78) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492473 0.96 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL203373 0.96 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL9097509 0.96 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2042 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184603-A Diamine monomer containing piperazine unit, polyimide acid salt separation membrane, and preparation method and application thereof 天津科技大学 2024-06-14 CN claimed
US-20240182645-A1 POLY(AMIC ACID) COMPOSITION, POLYIMIDE COMPOSITION, ADHESIVE, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2024-06-06 US claimed
CN-117701232-A Low-dielectric non-fluorine modified polyimide and preparation method and application thereof 华烁科技股份有限公司 2024-03-15 CN claimed
CN-117700740-A Polyimide containing benzoxazine suspension side group and preparation method and application thereof 华烁科技股份有限公司 2024-03-15 CN claimed
CN-117384482-A Non-fluorine modified polyimide, low-dielectric flexible copper-clad plate and preparation method thereof 华烁电子材料(武汉)有限公司 2024-01-12 CN claimed
CN-117120511-A Polyamic acid composition, polyimide composition, adhesive, and laminate 三井化学株式会社 2023-11-24 CN claimed
CN-115583889-A Diamine, liquid crystal aligning agent, and preparation method and application thereof 波米科技有限公司 2023-01-10 CN claimed
CN-115322522-A Polythioetherimide modified epoxy resin and preparation method thereof 中国科学院宁波材料技术与工程研究所 2022-11-11 CN claimed
WO-2022210321-A1 POLY(AMIC ACID) COMPOSITION, POLYIMIDE COMPOSITION, ADHESIVE, AND LAYERED PRODUCT 三井化学株式会社 2022-10-06 WO claimed
CN-111793237-B Production method of rigid polyimide foam material 贵州航天天马机电科技有限公司 2022-06-21 CN claimed
US-5276132-A Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-01-04 US claimed
EP-0148534-B1 BISMALEIMIDES AND PREPREG RESINS THEREFROM AMOCO CORPORATION (US) 1989-03-15 EP claimed
US-4618714-A NITRATION, REDUCTION, DECHLORINATION OF CHLORONITROBENZOPHENONES OBTAINED FROM A NITROBENZOYL CHLORIDE AND CHLOROBENZENE MITSUI TOATSU CHEMICALS, INC. (JP) 1986-10-21 US claimed
US-4556738-A CATALYTICALLY REDUCING AND DEHALOGENATING A DINITROBENZOPHENONE MITSUI TOATSU CHEMICALS, INC. (JP) 1985-12-03 US claimed
EP-0148534-A1 Bismaleimides and prepreg resins therefrom AMOCO CORPORATION (US) 1985-07-17 EP claimed
US-4497935-A RUBBER-MODIFIED MAIC ACID PREPOLYMER THE UNITES STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1985-02-05 US claimed
US-4389504-A AROMATIC AMINE CAPPED ACRYLONITRILE-BUTADIENE COPOLYMER OR SILICONE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION OFFICE OF GENERAL COUNSEL-CODE GP (US) 1983-06-21 US claimed
US-4284461-A ETHER SOLVENTS, SOLUTION POLYMERIZATION NASA 1981-08-18 US claimed
US-4094862-A 3,3',4,4'-BENZOPHENONE TETRACARBOXYLIC DIANHYDRIDE, 3,3'-DIAMINOBENZOPHENONE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1978-06-13 US claimed
US-4065345-A HIGH MOLECULAR WEIGHT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1977-12-27 US claimed