SCHEMBL17744847

SCHEMBL17744847

Nc1ccc(C(=O)c2ccc(C(=O)c3cccc(N)c3)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.81
NPC1 O15118 1/20 0.68
MITF O75030 1/20 0.68
LMNA P02545 1/20 0.68
POLB P06746 1/20 0.68
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
CA9 Q16790 2/20 0.63
ATM Q13315 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NOX1 Q9Y5S8 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HSD17B10 Q99714 1/20 0.49
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5832368 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29037240 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL5114913 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL127545 1.00 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
SCHEMBL23162465 0.98 PBRM1 (0.78) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL10904319 0.98 PBRM1 (0.78) PBRM1NPC1MITFLMNAPOLB
SCHEMBL17744842 0.98 PBRM1 (0.78) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492473 0.96 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL203373 0.96 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL9097509 0.96 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
US-20210355269-A1 EPOXY RESIN COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2021-11-18 US disclosed
US-11059937-B2 Epoxy resin THE BOEING COMPANY (US) 2021-07-13 US disclosed
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
US-20190248953-A1 EPOXY RESIN THE BOEING COMPANY 2019-08-15 US disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
WO-2018018070-A1 EPOXY RESIN THE BOEING COMPANY (US) 2018-02-01 WO disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718707-B2 Epoxy resin EPHX2, EPHX1, CBR1 PBRM1 1380/4885NPC1 4576/4885MITF 4153/4885
US-20210355269-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 PBRM1 1380/4885NPC1 4576/4885MITF 4153/4885
US-20190248953-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 PBRM1 1380/4885NPC1 4576/4885MITF 4153/4885
US-11059937-B2 Epoxy resin EPHX2, EPHX1, CBR1 PBRM1 1380/4885NPC1 4576/4885MITF 4153/4885
US-20230312812-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 PBRM1 1380/4885NPC1 4576/4885MITF 4153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.