Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918472 | 0.85 | CYP19A1 (0.55) | HDAC1HDAC8HTR1AHTR1DHTR1B | |
| SCHEMBL28853829 | 0.83 | PTGS2 (0.53) | HDAC1HDAC8CYP19A1CYP17A1CYP11B1 | |
| Sulfuric Acid SCHEMBL9705330 | 0.81 | CYP19A1 (0.51) | HDAC1HDAC8HTR1AHTR1DHTR1B | |
| SCHEMBL9269708 | 0.80 | HDAC1 (0.51) | HDAC1HDAC8CYP19A1CYP17A1CYP11B1 | |
| SCHEMBL1650349 | 0.80 | CA12 (0.49) | HDAC1HDAC8CYP19A1CYP17A1CYP11B1 | |
| SCHEMBL9800386 | 0.79 | HDAC1 (0.45) | HDAC1HDAC8CYP19A1CYP17A1CYP11B1 | |
| SCHEMBL8666600 | 0.77 | HDAC1 (0.55) | HDAC1HDAC8CYP19A1CYP17A1CYP11B1 | |
| SCHEMBL9772878 | 0.77 | HDAC1 (0.48) | HDAC1HDAC8CYP19A1BPTFCA12 | |
| SCHEMBL14756111 | 0.76 | SLC6A2 (0.51) | HDAC1HDAC8CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL1457933 | 0.75 | CYP19A1 (0.48) | HDAC1HDAC8HTR1AHTR1BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004580-A2 | PROCESS FOR PREPARING INDOLE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2010-01-14 | — | — | WO | claimed |
| WO-2009016466-A2 | A PROCESS FOR THE PREPARATION OF NARATRIPTAN HYDROCHLORIDE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2009-02-05 | — | — | WO | claimed |
| WO-2008072257-A2 | PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-19 | — | — | WO | claimed |
| WO-2008056378-A2 | NOVEL PROCESS FOR THE PREPARATION OF NARATRIPTAN HYDROCHLORIDE | NATCO PHARMA LIMITED (IN) | 2008-05-15 | — | — | WO | claimed |
| CN-115611854-B | New method for preparing naratriptan and derivatives thereof | 天津师范大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115611854-A | New method for preparing naratriptan and derivatives thereof | 天津师范大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-113754631-B | Heteroaryl method of indole | 中国科学院理化技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-113754631-A | Heteroaryl method of indole | 中国科学院理化技术研究所 | 2021-12-07 | — | — | CN | disclosed |
| US-8735589-B2 | Process for the synthesis of naratriptan | CIPLA LIMITED (IN) | 2014-05-27 | — | — | US | disclosed |
| US-8735589-B2 | Process for the synthesis of naratriptan | CIPLA LIMITED (IN) | 2014-05-27 | — | — | US | disclosed |
| US-8735589-B2 | Process for the synthesis of naratriptan | CIPLA LIMITED (IN) | 2014-05-27 | — | — | US | disclosed |
| EP-2467373-B1 | A PROCESS FOR THE SYNTHESIS OF NARATRIPTAN | CIPLA LTD (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2008072257-A2 | PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008056378-A2 | NOVEL PROCESS FOR THE PREPARATION OF NARATRIPTAN HYDROCHLORIDE | NATCO PHARMA LIMITED (IN) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008056378-A2 | NOVEL PROCESS FOR THE PREPARATION OF NARATRIPTAN HYDROCHLORIDE | NATCO PHARMA LIMITED (IN) | 2008-05-15 | — | — | WO | disclosed |
| EP-0303507-B1 | INDOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 1993-07-28 | — | — | EP | disclosed |
| US-4997841-A | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-03-05 | — | — | US | disclosed |
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |
| EP-0303507-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |
| CN-85104233-A | Chemical compound | — | 1987-01-07 | — | — | CN | disclosed |