Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428344 | 0.80 | SLC6A2 (0.37) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL4566612 | 0.80 | CYP19A1 (0.45) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL9269708 | 0.79 | HDAC1 (0.51) | CYP19A1HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL28853829 | 0.79 | PTGS2 (0.53) | CYP19A1HDAC1HDAC8CA12CA1 | |
| SCHEMBL1650349 | 0.79 | CA12 (0.49) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL12384488 | 0.79 | HDAC1 (0.57) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL6099420 | 0.78 | NPC1 (0.55) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL14207475 | 0.77 | CYP19A1 (0.45) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL4414373 | 0.77 | HDAC1 (0.52) | CYP19A1HDAC1HDAC8SLC6A2SLC6A3 | |
| SCHEMBL8666600 | 0.76 | HDAC1 (0.55) | CYP19A1HDAC1HDAC8NPC1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254720-B2 | Methods and systems for designing and/or characterizing soluble lipidated ligand agents | ON TARGET THERAPEUTICS LLC (US) | 2022-02-22 | — | — | US | disclosed |
| US-20190135882-A1 | Methods and Systems for Designing and/or Characterizing Soluble Lipidated Ligand Agents | ON TARGET THERAPEUTICS LLC | 2019-05-09 | — | — | US | disclosed |
| US-8633239-B2 | Process for the preparation of eletriptan | BIOPHORE INDIA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-01-21 | — | — | US | disclosed |
| US-8633239-B2 | Process for the preparation of eletriptan | BIOPHORE INDIA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-01-21 | — | — | US | disclosed |
| EP-2349998-B1 | A NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | BIOPHORE INDIA PHARMACEUTICALS PVT LTD (IN) | 2013-07-17 | — | — | EP | disclosed |
| EP-2349998-B1 | A NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | BIOPHORE INDIA PHARMACEUTICALS PVT LTD (IN) | 2013-07-17 | — | — | EP | disclosed |
| CN-102414198-A | Synthesis of 3- { [ (2R) -1-methylpyrrolidin-2-yl ] methyl } -5- [2- (phenylsulfonyl) ethyl ] -1H-indole | ITALIANA SINT SPA | 2012-04-11 | — | — | CN | disclosed |
| WO-2012004811-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-01-12 | — | — | WO | disclosed |
| US-20110207943-A1 | NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | BIOPHORE INDIA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2011-08-25 | — | — | US | disclosed |
| US-20110207943-A1 | NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | BIOPHORE INDIA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2011-08-25 | — | — | US | disclosed |
| EP-2349998-A2 | A NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | Biophore India Pharmaceuticals Pvt. Ltd. (IN) | 2011-08-03 | — | — | EP | disclosed |
| US-20110166364-A1 | SYNTHESIS OF 3--5-[2-(PHENYLSULFONYL)ETHYL]-1H-INDOLE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2011-07-07 | — | — | US | disclosed |
| WO-2011024039-A1 | SYNTHESIS OF NOVEL 5-(2-(PHENYLSULFONYL)ETHYL)-1H-INDOLE DERIVATIVES | POTLURI RAMESH BABU (IN) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011024039-A1 | SYNTHESIS OF NOVEL 5-(2-(PHENYLSULFONYL)ETHYL)-1H-INDOLE DERIVATIVES | POTLURI RAMESH BABU (IN) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011024039-A1 | SYNTHESIS OF NOVEL 5-(2-(PHENYLSULFONYL)ETHYL)-1H-INDOLE DERIVATIVES | POTLURI RAMESH BABU (IN) | 2011-03-03 | — | — | WO | disclosed |
| WO-2010049952-A2 | A NOVEL PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED INDOLE DERIVATIVES | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010049952-A2 | A NOVEL PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED INDOLE DERIVATIVES | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254720-B2 | Methods and systems for designing and/or characterizing soluble lipidated ligand agents | LDLR, HDLBP, LIPG | CYP19A1 2915/4885HDAC1 2711/4885HDAC8 2011/4885 |
| US-20190135882-A1 | Methods and Systems for Designing and/or Characterizing Soluble Lipidated Ligand Agents | LDLR, HDLBP, LIPG | CYP19A1 2915/4885HDAC1 2711/4885HDAC8 2011/4885 |
| US-20110207943-A1 | NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | HTR3C, HTR3A, HTR1A | CYP19A1 722/4885HDAC1 1433/4885HDAC8 1110/4885 |
| US-20110166364-A1 | SYNTHESIS OF 3--5-[2-(PHENYLSULFONYL)ETHYL]-1H-INDOLE | TMPRSS15, PEPD, DPP9 | CYP19A1 1254/4885HDAC1 328/4885HDAC8 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.