SCHEMBL12757656

SCHEMBL12757656

COc1ccc(Nc2ccc3c(O)c(N=Nc4cc(C)c(N=Nc5cc(C)c(N=Nc6ccc(OC)cc6S(=O)(=O)O)cc5OC)cc4OC)c(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.68
▸ PRMT1 Q99873 2/20 0.49
▸ CARM1 Q86X55 1/20 0.49
▸ CD40 P25942 1/20 0.48
▸ CD40LG P29965 1/20 0.48
▸ PHLPP2 Q6ZVD8 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.44
▸ HIF1A Q16665 1/20 0.44
▸ PTPN1 P18031 2/20 0.44
▸ PRMT3 O60678 1/20 0.41
▸ EP300 Q09472 1/20 0.41
▸ PRMT6 Q96LA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757648 1.00 ENPP2 (0.68) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL12757652 0.96 ENPP2 (0.61) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL14024915 0.95 ENPP2 (0.65) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL12757450 0.94 ENPP2 (0.72) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL15386685 0.94 ENPP2 (0.72) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL14773719 0.94 ENPP2 (0.72) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL20735300 0.94 ENPP2 (0.68) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL14773624 0.92 ENPP2 (0.60) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL12757650 0.92 ENPP2 (0.60) ENPP2PRMT1CARM1CD40CD40LG
SCHEMBL12757665 0.92 ENPP2 (0.73) ENPP2PRMT1CARM1CD40CD40LG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940059-B2 Azo compound and dye polarizing film containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-01-27 — — US disclosed
US-20110089383-A1 Azo Compound And Dye Polarizing Film Containing The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-04-21 — — US disclosed
US-20100257678-A1 Azo compound and dye polarizing film containing the same POLATECHNO CO., LTD. (JP) 2010-10-14 — — US disclosed
Send feedback