SCHEMBL12757650

SCHEMBL12757650

COc1ccc(N=Nc2cc(C)c(N=Nc3cc(C)c(N=Nc4c(S(=O)(=O)O)cc5cc(Nc6ccc(C)cc6)ccc5c4O)cc3C)cc2C)c(S(=O)(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 9/20 0.60
▸ ALDH1A1 P00352 1/20 0.51
▸ HIF1A Q16665 1/20 0.51
▸ CD40 P25942 1/20 0.50
▸ CD40LG P29965 1/20 0.50
▸ PRMT1 Q99873 2/20 0.47
▸ CARM1 Q86X55 1/20 0.47
▸ PRMT3 O60678 1/20 0.43
▸ EP300 Q09472 1/20 0.43
▸ PRMT6 Q96LA8 1/20 0.43
▸ PHLPP2 Q6ZVD8 2/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SNCA P37840 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757652 0.96 ENPP2 (0.61) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL11913411 0.94 ENPP2 (0.68) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL14773624 0.93 ENPP2 (0.60) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL12757648 0.92 ENPP2 (0.68) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL12757656 0.92 ENPP2 (0.68) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL15935780 0.91 ENPP2 (0.56) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL14024915 0.89 ENPP2 (0.65) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL14024916 0.89 ENPP2 (0.62) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL12757453 0.88 ENPP2 (0.63) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL13088675 0.88 ENPP2 (0.48) ENPP2ALDH1A1HIF1ACD40CD40LG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 — — US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 — — US disclosed
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 — — WO disclosed
US-8940059-B2 Azo compound and dye polarizing film containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-01-27 — — US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 — — US disclosed
US-20110089383-A1 Azo Compound And Dye Polarizing Film Containing The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-04-21 — — US disclosed
US-20100257678-A1 Azo compound and dye polarizing film containing the same POLATECHNO CO., LTD. (JP) 2010-10-14 — — US disclosed
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