SCHEMBL14024915

SCHEMBL14024915

COc1ccc(N=Nc2cc(C)c(N=Nc3cc(OC)c(N=Nc4c(S(=O)(=O)O)cc5cc(Nc6ccc(N)cc6)ccc5c4O)cc3OC)cc2C)c(S(=O)(=O)O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 9/20 0.65
▸ PHLPP2 Q6ZVD8 1/20 0.51
▸ CD40 P25942 1/20 0.46
▸ CD40LG P29965 1/20 0.46
▸ PRMT1 Q99873 2/20 0.45
▸ CARM1 Q86X55 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ PTPN1 P18031 2/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ PRMT3 O60678 1/20 0.39
▸ EP300 Q09472 1/20 0.39
▸ PRMT6 Q96LA8 1/20 0.39
▸ SUMO2 P61956 1/20 0.39
▸ SUMO1 P63165 1/20 0.39
▸ SENP7 Q9BQF6 1/20 0.39
▸ SENP3 Q9H4L4 1/20 0.39
▸ SENP2 Q9HC62 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757648 0.95 ENPP2 (0.68) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL12757656 0.95 ENPP2 (0.68) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL12757652 0.91 ENPP2 (0.61) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL13880568 0.91 ENPP2 (0.59) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL14001676 0.90 ENPP2 (0.53) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL15386685 0.90 ENPP2 (0.72) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL14773719 0.90 ENPP2 (0.72) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL12757450 0.90 ENPP2 (0.72) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL20735300 0.89 ENPP2 (0.68) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL12757650 0.89 ENPP2 (0.60) ENPP2PHLPP2CD40CD40LGPRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445822-B2 Azo compounds and dye-type polarizing films or plates containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-04 — — US disclosed
US-20080094549-A1 Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-04-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080094549-A1 Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same CRY1, SCO2, SPR ENPP2 1986/4885PHLPP2 695/4885CD40 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback