Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1417761 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7306927 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7309807 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL8431293 | 0.91 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL8664938 | 0.91 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL2626703 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7309272 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL5809049 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7889792 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL9137641 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115364822-A | Preparation method and application of MOFs material | 广东美的白色家电技术创新中心有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-112337419-B | Preparation method of 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester | 浙江花蝶染料化工有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112337419-A | Preparation method of 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester | 浙江花蝶染料化工有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-111205229-A | Preparation method of 2-propyl-4, 5-imidazole dicarboxylic acid diethyl ester | 山东金城柯瑞化学有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-102070533-B | New method for synthesizing 4-(1-hydroxyl-1-methyl ethyl)-2-propyl imidazole-5-carboxylic acid ethyl ester | SHANGHAI SYNCORES TECHNOLOGIES INC | 2015-06-10 | — | — | CN | claimed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-115364822-B | Preparation method and application of MOFs material | 广东美的白色家电技术创新中心有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116813552-A | Recovery and purification process of olmesartan intermediate impurities | 江苏阿尔法药业股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109081812-B | 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester monohydrate | 黄冈鲁班药业股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| CN-112337419-B | Preparation method of 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester | 浙江花蝶染料化工有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113336706-B | Synthetic method for preparing olmesartan medoxomil intermediate by continuous flow | 拓信达(启东)医药生物科技有限公司 | 2022-04-22 | — | — | CN | disclosed |
| WO-2006029057-A1 | PURIFICATION OF OLMESARTAN MEDOXOMIL | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-03-16 | — | — | WO | disclosed |
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| EP-0545912-B1 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| US-5932741-A | TREATING ILLNESSES RESULTING FROM ABNORMAL STIMULATION OF ENDOTHELIN RECEPTORS | HOECHST MARION ROUSSEL (FR) | 1999-08-03 | — | — | US | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |