Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275935 | 0.91 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHTTRECQL | |
| Hydrochloric Acid SCHEMBL1417761 | 0.89 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7306927 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL8431293 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL2626703 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL651 | 0.84 | PIN1 (0.42) | CYP1A2CYP2C19POLBMAPK1 | |
| SCHEMBL5809049 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7309807 | 0.82 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL9137641 | 0.80 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL4356883 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813552-A | Recovery and purification process of olmesartan intermediate impurities | 江苏阿尔法药业股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109081812-B | 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester monohydrate | 黄冈鲁班药业股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112337419-B | Preparation method of 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester | 浙江花蝶染料化工有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113336706-B | Synthetic method for preparing olmesartan medoxomil intermediate by continuous flow | 拓信达(启东)医药生物科技有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-113336706-A | Synthetic method for preparing olmesartan medoxomil intermediate by continuous flow | 拓信达(启东)医药生物科技有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-112337419-A | Preparation method of 4- (1-hydroxy-1-methylethyl) -2-propylimidazole-5-carboxylic acid ethyl ester | 浙江花蝶染料化工有限公司 | 2021-02-09 | — | — | CN | disclosed |
| WO-2020043025-A1 | HYDRATE OF 4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYLIMIDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER | 黄冈鲁班药业股份有限公司 | 2020-03-05 | — | — | WO | disclosed |
| US-5811444-A | IMIDAZOLE DERIVATIVES | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |