Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7885680 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7883522 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7309272 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL30663426 | 0.86 | NPSR1 (0.41) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL1275935 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7885549 | 0.83 | LMNA (0.40) | ALDH1A1KDM4EHPGDHTTRECQL | |
| Hydrochloric Acid SCHEMBL1417761 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHTTRECQL | |
| Hydrochloric Acid SCHEMBL7889797 | 0.82 | LMNA (0.40) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7309807 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7885220 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573218-B1 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO CO (JP) | 2001-03-07 | — | — | EP | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0573218-A2 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-12-08 | — | — | EP | disclosed |