Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | RXRG | P48443 | 3/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13718200 | 0.90 | RXRA (0.49) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL1276478 | 0.89 | MAPT (0.50) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL930474 | 0.87 | MRGPRX4 (0.55) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL1275782 | 0.83 | PTGDR2 (0.54) | PTGER1PTGER4PTGER3PTGER2TP53 | |
| SCHEMBL13718412 | 0.79 | LMNA (0.49) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL1276664 | 0.79 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2HPGDPOLBKDM4E | |
| SCHEMBL29955503 | 0.77 | PTGDR2 (0.62) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL8409609 | 0.76 | PTGER1 (0.62) | RXRARXRBRXRGPTGER1PTGER4 | |
| SCHEMBL931584 | 0.76 | RXRA (0.59) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL930595 | 0.76 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028752-A1 | NOVEL BIS(FORMYLPHENYL) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED FROM THE SAME | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028752-A1 | NOVEL BIS(FORMYLPHENYL) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED FROM THE SAME | PAH, PCBP1, MLLT1 | RXRA 1729/4885RXRB 1101/4885RXRG 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.