SCHEMBL1276013

SCHEMBL1276013

COc1cccc(C(=O)Cc2ccccc2)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.60
RAB9A P51151 3/20 0.60
TP53 P04637 2/20 0.54
USP2 O75604 1/20 0.54
HIF1A Q16665 2/20 0.53
KDM4E B2RXH2 2/20 0.53
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.50
SLC6A12 P48065 1/20 0.50
GLA P06280 1/20 0.50
LMNA P02545 2/20 0.49
PDE4D Q08499 2/20 0.49
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GAA P10253 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3282912 0.87 NPC1 (0.63) NPC1RAB9ATP53USP2KMT2A
SCHEMBL29861033 0.87 NPC1 (0.63) NPC1RAB9ATP53USP2KMT2A
SCHEMBL17838555 0.85 HIF1A (0.58) NPC1RAB9ATP53USP2HIF1A
SCHEMBL8800692 0.83 USP2 (0.52) NPC1RAB9ATP53USP2HIF1A
SCHEMBL4684698 0.82 MAPT (0.62) NPC1RAB9ATP53USP2HIF1A
SCHEMBL28924750 0.81 NPC1 (0.56) NPC1RAB9ATP53USP2KDM4E
SCHEMBL5617204 0.80 HPGD (0.54) NPC1RAB9ATP53KDM4EKMT2A
SCHEMBL27598682 0.80 CA12 (0.58) NPC1RAB9ATP53USP2KMT2A
SCHEMBL3661643 0.80 HPGD (0.54) NPC1RAB9ATP53KDM4EKMT2A
SCHEMBL8318992 0.80 ALDH1A1 (0.49) NPC1RAB9ATP53USP2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017174545-A1 PHOTOCURABLE POLYMERS, PHOTOCURABLE POLYMER COMPOSITIONS AND LITHOGRAPHIC PROCESSES INCLUDING THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-10-12 WO claimed
US-7354698-B2 Imprint lithography ASML NETHERLANDS B.V. (NL) 2008-04-08 US claimed
US-20060154179-A1 Imprint lithography ASML NETHERLANDS B. V. (NL) 2006-07-13 US claimed
WO-1997000736-A1 METHOD OF REINFORCING FOOTWEAR UPPER MATERIALS HENKEL CORPORATION (US) 1997-01-09 WO claimed
EP-3847220-B1 UV-CURABLE HOT MELT ADHESIVE COMPOSITIONS FOR FLOORING APPLICATIONS BASF SE (DE) 2025-03-05 EP disclosed
CN-118994491-A Photocurable composition for stereolithography, stereolithography method using the same, polymer assembly formed by the stereolithography method, and device comprising the polymer assembly 罗杰斯公司 2024-11-22 CN disclosed
CN-113906066-B Photocurable composition for stereolithography, stereolithography method using the same, polymer assembly formed by the stereolithography method, and device comprising the polymer assembly 罗杰斯公司 2024-10-01 CN disclosed
EP-4302170-A1 SYSTEMS FOR THERMAL MANAGEMENT AND METHODS THEREOF Holo, Inc. (US) 2024-01-10 EP disclosed
WO-2023164445-A1 CONDUCTIVE ARTICLES AND METHODS FOR ADDITIVE MANUFACTURING THEREOF PPG INDUSTRIES OHIO, INC. (US) 2023-08-31 WO disclosed
EP-4217435-A1 CURABLE SILICONE-(METH)ACRYLATE COMPOSITION AND METHODS FOR ITS PREPARATION AND USE Dow Silicones Corporation (US) 2023-08-02 EP disclosed
CN-114667466-A Optical laminate and flexible display device 住友化学株式会社 2022-06-24 CN disclosed
EP-3924320-A1 METHODS AND SYSTEMS FOR THREE-DIMENSIONAL PRINTING Holo, Inc. (US) 2021-12-22 EP disclosed
EP-0868223-A1 RADIATION-CURED EDGE-MASKING PROCESS FOR HIGH SPEED ELECTROGALVANIZING USX ENGINEERS AND CONSULTANTS, INC. (US) 1998-10-07 EP disclosed
WO-1998001778-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1998-01-15 WO disclosed
WO-1997047671-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-12-18 WO disclosed
WO-1997022418-A1 RADIATION-CURED EDGE-MASKING PROCESS FOR HIGH SPEED ELECTROGALVANIZING USX ENGINEERS AND CONSULTANTS, INC. (US) 1997-06-26 WO disclosed
EP-0418870-A2 Radiation sensitive polymer composition TORAY INDUSTRIES, INC. (JP) 1991-03-27 EP disclosed
US-4954269-A TREATING TEXTILES TO INCREASE THE WATER ABSORPTIVITY DOW CORNING CORPORATION (US) 1990-09-04 US disclosed
US-4518472-A COMPOUND CONTAINING AT LEAST THREE (METH)ACRYLOYLOXY GROUPS, PHOTOSENSITIZER, EMULSION-TYPE CROSSLINKED POLYMER MITSUBISHI RAYON COMPANY LTD. (JP) 1985-05-21 US disclosed
US-4478876-A BLEND OF ACRYLATE MONOMER, COLLOIDAL SILICA, ACRYLOXY FUNCTIONAL SILANE, AND PHOTOINITIATORS GENERAL ELECTRIC COMPANY (US) 1984-10-23 US disclosed