Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29861033 | 1.00 | NPC1 (0.63) | NPC1TP53USP2GLAHPGD | |
| SCHEMBL19419913 | 0.90 | TP53 (0.56) | NPC1TP53USP2GLAHPGD | |
| SCHEMBL6281987 | 0.87 | POLB (0.63) | NPC1TP53USP2GLAHPGD | |
| SCHEMBL1276013 | 0.87 | NPC1 (0.60) | NPC1TP53USP2GLAHPGD | |
| Bromide SCHEMBL8370980 | 0.85 | POLB (0.62) | NPC1TP53USP2GLAHPGD | |
| SCHEMBL8968394 | 0.84 | NPC1 (0.50) | NPC1TP53USP2GLAHPGD | |
| SCHEMBL6203601 | 0.83 | ABCB1 (0.62) | NPC1TP53GLAHPGDRAB9A | |
| SCHEMBL8968389 | 0.83 | NPC1 (0.49) | NPC1TP53USP2GLAHPGD | |
| SCHEMBL17637149 | 0.82 | HSD11B1 (0.63) | NPC1TP53USP2RAB9ASMN1; SMN2 | |
| SCHEMBL6151260 | 0.82 | USP2 (0.47) | NPC1TP53USP2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113755862-B | Method for preparing aromatic alpha-diketone compound by electrochemical oxidation | 西南大学 | 2022-08-19 | — | — | CN | claimed |
| CN-113755862-A | Method for preparing aromatic alpha-diketone compound by electrochemical oxidation | 西南大学 | 2021-12-07 | — | — | CN | claimed |
| CN-113755862-B | Method for preparing aromatic alpha-diketone compound by electrochemical oxidation | 西南大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-113755862-A | Method for preparing aromatic alpha-diketone compound by electrochemical oxidation | 西南大学 | 2021-12-07 | — | — | CN | disclosed |
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
| WO-2017106930-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2017-06-29 | — | — | WO | disclosed |
| EP-2018364-B1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN INC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-7709507-B2 | Therapeutic fluoroethyl ureas | ALLERGAN, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. | 2007-11-22 | — | — | US | disclosed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| EP-1032568-A4 | PROCESS FOR THE PREPARATION OF ISOFLAVONES | UNIV MICHIGAN STATE (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1032568-A1 | PROCESS FOR THE PREPARATION OF ISOFLAVONES | MICHIGAN STATE UNIVERSITY (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000015627-A1 | PROCESS FOR THE PREPARATION OF ISOFLAVONES | MICHIGAN STATE UNIVERSITY (US) | 2000-03-23 | — | — | WO | disclosed |
| EP-0221368-A2 | Substituted 1,1,2-triphenyl-1-butene | ASTA Pharma Aktiengesellschaft (DE) | 1987-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | ERCC4, NQO1, ERCC5 | NPC1 316/4885TP53 2396/4885USP2 4764/4885 |
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | SLC14A1, MAPT, UTS2R | NPC1 288/4885TP53 154/4885USP2 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.