Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901235 | 0.85 | HIF1A (0.47) | ALDH1A1HIF1AKDM4EUSP2TP53 | |
| SCHEMBL7823257 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10958946 | 0.80 | GAA (0.52) | ALDH1A1HIF1AUSP2TP53SMN1; SMN2 | |
| SCHEMBL1276013 | 0.80 | NPC1 (0.60) | ALDH1A1HIF1AKDM4EUSP2TP53 | |
| SCHEMBL7046039 | 0.79 | CTSV (0.44) | ALDH1A1HIF1AUSP2TP53SMN1; SMN2 | |
| SCHEMBL10998628 | 0.79 | CTSV (0.49) | SMN1; SMN2LMNAGAANPC1RAB9A | |
| SCHEMBL3282912 | 0.79 | NPC1 (0.63) | ALDH1A1USP2TP53SMN1; SMN2LMNA | |
| SCHEMBL29861033 | 0.79 | NPC1 (0.63) | ALDH1A1USP2TP53SMN1; SMN2LMNA | |
| SCHEMBL12950516 | 0.79 | HSP90AA1 (0.55) | ALDH1A1HIF1AKDM4EUSP2TP53 | |
| SCHEMBL4684698 | 0.78 | MAPT (0.62) | HIF1AKDM4EUSP2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087027-B | Preparation process of polyhydroxy isoflavone | COLLEGE OF MILITARY PREVENTIVE MEDICINE THIRD MILITARY MEDICAL UNIVERSITY OF PLA | 2014-11-19 | — | — | CN | claimed |
| CN-103087027-A | Preparation process of polyhydroxy isoflavone | MILITARY PREVENTION MEDICAL COLLEGE THIRD MILITARY MEDICAL UNIVERSITY OF PLA | 2013-05-08 | — | — | CN | claimed |
| CN-103087027-B | Preparation process of polyhydroxy isoflavone | COLLEGE OF MILITARY PREVENTIVE MEDICINE THIRD MILITARY MEDICAL UNIVERSITY OF PLA | 2014-11-19 | — | — | CN | disclosed |
| CN-103087027-A | Preparation process of polyhydroxy isoflavone | MILITARY PREVENTION MEDICAL COLLEGE THIRD MILITARY MEDICAL UNIVERSITY OF PLA | 2013-05-08 | — | — | CN | disclosed |
| EP-0888346-A1 | CORALYNE ANALOGS AS TOPOISOMERASE INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997029106-A1 | CORALYNE ANALOGS AS TOPOISOMERASE INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1997-08-14 | — | — | WO | disclosed |