SCHEMBL1276156

SCHEMBL1276156

CCCCCCCCCCCCCCCCCCO[Si](=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.45
LPAR2 Q9HBW0 5/20 0.45
LPAR1 Q92633 2/20 0.45
NAAA Q02083 1/20 0.45
CES2 O00748 1/20 0.43
EPHX1 P07099 1/20 0.42
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 2/20 0.41
CA1 P00915 5/20 0.40
CA2 P00918 5/20 0.40
CA9 Q16790 5/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1157409 1.00 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL76192 1.00 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL543796 1.00 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL2537730 1.00 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
Ammonia Solution, Strong SCHEMBL4405541 0.95 LPAR3 (0.40) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL76346 0.90
SCHEMBL10631643 0.86 ALDH1A1 (0.39) LPAR3LPAR2LPAR1NAAACES2
Ethylene Glycol SCHEMBL8779018 0.84 TSHR (0.44) MEN1THRBHTTKMT2AMAPT
Urea SCHEMBL11603088 0.82 ALDH1A1 (0.41) NAAAMAPTTSHRCA1CA2
SCHEMBL9895427 0.81 ALDH1A1 (0.46) LPAR3LPAR2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332119-A1 NOVEL ANTI-INFLAMMATORY COMPOSITION AND USE THEREOF ASK CO., LTD. (KR) 2025-10-30 US disclosed
WO-2024150964-A1 NOVEL ANTI-INFLAMMATORY COMPOSITION AND USE THEREOF 주식회사 에스크컴퍼니 2024-07-18 WO disclosed
US-8460895-B2 Method for producing recombinant proteins with a constant content of pCO2 in the medium HOFFMANN-LA ROCHE INC. (US) 2013-06-11 US disclosed
EP-2283120-B1 METHOD FOR PRODUCING RECOMBINANT PROTEINS WITH A CONSTANT CONTENT OF PCO2 IN THE MEDIUM HOFFMANN LA ROCHE (CH) 2013-01-02 EP disclosed
US-20110159539-A1 METHOD FOR PRODUCING RECOMBINANT PROTEINS WITH A CONSTANT CONTENT OF PCO2 IN THE MEDIUM F. HOFFMANN-LA ROCHE AG (CH) 2011-06-30 US disclosed
EP-2283120-A1 METHOD FOR PRODUCING RECOMBINANT PROTEINS WITH A CONSTANT CONTENT OF PCO2 IN THE MEDIUM F. Hoffmann-La Roche AG (CH) 2011-02-16 EP disclosed
CN-101970646-A Method for producing recombinant proteins with a constant content of pco2 in the medium HOFFMANN LA ROCHE 2011-02-09 CN disclosed
WO-2010097434-A1 PROCESS FOR THE PREPARATION OF CYCLODEXTRINS COMPOSED OF MORE THAN EIGHT GLUCOSE UNITS UNIVERSITÄT LEIPZIG (DE) 2010-09-02 WO disclosed
EP-2223942-A1 Process for the preparation of cyclodextrins composed of more than eight glucose units Universität Leipzig (DE) 2010-09-01 EP disclosed
WO-2009112250-A1 METHOD FOR PRODUCING RECOMBINANT PROTEINS WITH A CONSTANT CONTENT OF PCO2 IN THE MEDIUM F. HOFFMANN-LA ROCHE AG (CH) 2009-09-17 WO disclosed
US-5110960-A Tetracycline, anthracycline and anthraquinone antibiotics BRISTOL-MYERS COMPANY (US) 1992-05-05 US disclosed
EP-0277621-B1 ANTIFUNGAL ANTIBIOTICS Bristol-Myers Squibb Company (US) 1992-02-05 EP disclosed
US-4990497-A Antifungal antibiotics OKI TOSHIKAZU (JP) 1991-02-05 US disclosed
EP-0277621-A1 Antifungal antibiotics Bristol-Myers Squibb Company (US) 1988-08-10 EP disclosed