Ethylene Glycol

Ethylene Glycol

SCHEMBL8779018

CCCCO[Si](=O)O.OCCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.35
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.34
ACHE P22303 4/20 0.34
HPGD P15428 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76346 0.93
SCHEMBL10631643 0.88 ALDH1A1 (0.39) TSHRALDH1A1ATMCYP3A4HPGD
Ethylene Glycol SCHEMBL11572656 0.85
Urea SCHEMBL11603088 0.84 ALDH1A1 (0.41) TSHRALDH1A1SMN1; SMN2ATMMAPT
SCHEMBL1276156 0.84 LPAR3 (0.45) TSHRMEN1KMT2ATHRBHTT
Ammonia Solution, Strong SCHEMBL4405541 0.84 LPAR3 (0.40) TSHRMEN1KMT2ATHRBHTT
SCHEMBL1157409 0.84 LPAR3 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL2537730 0.84 LPAR3 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL76192 0.84 LPAR3 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL543796 0.84 LPAR3 (0.45) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535474-B1 Method of fabricating a single curved or double curved laminated window, especially for vehicles FLACHGLAS AG (DE) 1997-04-02 EP claimed