Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276156 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL2537730 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL76192 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL543796 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL1157409 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL76346 | 0.90 | — | — | |
| SCHEMBL10631643 | 0.86 | ALDH1A1 (0.39) | LPAR3LPAR2LPAR1NAAACES2 | |
| Ethylene Glycol SCHEMBL8779018 | 0.84 | TSHR (0.44) | CA1CA2MEN1THRBHTT | |
| Urea SCHEMBL11603088 | 0.82 | ALDH1A1 (0.41) | NAAACA1CA2MAPTTSHR | |
| SCHEMBL11330126 | 0.77 | TSHR (0.48) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948236-B1 | METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN | SPECIAL WATER PATENTS B V (NL) | 2021-03-03 | — | — | EP | disclosed |
| US-9499419-B2 | Methods and compositions for treatment of skin | Special Waters Patents B.V. (NL) | 2016-11-22 | — | — | US | disclosed |
| US-20090214628-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN | SPECIAL WATER PATENTS B.V. (NL) | 2009-08-27 | — | — | US | disclosed |
| EP-1948236-A2 | METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN | Naturalite Benelux B.V. (NL) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007099398-A2 | METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN | NATURALITE BENELUX B.V. (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-0814815-A4 | POLY(HYDROXY ACID)/POLYMER CONJUGATES FOR SKIN APPLICATIONS | FOCAL INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6261544-B1 | COPOLYMERS OF LINEAR, BRUSH, STAR, BRANCHED AND CROSSLINKING | FOCAL, INC. | 2001-07-17 | — | — | US | disclosed |
| US-5879688-A | Hydroxy-acid cosmetics | FOCAL, INC. (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0814815-A1 | POLY(HYDROXY ACID)/POLYMER CONJUGATES FOR SKIN APPLICATIONS | FOCAL, INC. (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5618850-A | Hydroxy-acid cosmetics | FOCAL, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| WO-1996029080-A1 | POLY(HYDROXY ACID)/POLYMER CONJUGATES FOR SKIN APPLICATIONS | FOCAL, INC. (US) | 1996-09-26 | — | — | WO | disclosed |