SCHEMBL12761602

SCHEMBL12761602

O=C(O)c1ccc(/N=N\c2ccc(/N=N\c3ccc(/C=C\c4ccc(/N=N\c5ccc(/N=N\c6ccc(C(=O)O)cc6)cc5)cc4S(=O)(=O)O)c(OSO)c3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAD1 O60671 1/20 0.46
▸ P2RY6 Q15077 1/20 0.46
▸ SENP2 Q9HC62 5/20 0.43
▸ SENP1 Q9P0U3 5/20 0.43
▸ SENP3 Q9H4L4 4/20 0.43
▸ SUMO2 P61956 3/20 0.43
▸ SUMO1 P63165 3/20 0.43
▸ SENP7 Q9BQF6 3/20 0.43
▸ CD69 Q07108 1/20 0.38
▸ TRPA1 O75762 1/20 0.38
▸ PHLPP2 Q6ZVD8 2/20 0.35
▸ POLB P06746 5/20 0.34
▸ KMT2A Q03164 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ NPC1 O15118 2/20 0.34
▸ ENPP2 Q13822 1/20 0.34
▸ MAPT P10636 5/20 0.33
▸ ALDH1A1 P00352 4/20 0.33
▸ TDP1 Q9NUW8 4/20 0.33
▸ KDM4E B2RXH2 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12761601 0.92 SENP2 (0.42) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12761600 0.91 SENP2 (0.44) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12847595 0.87 RAD1 (0.58) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12761609 0.85 SENP2 (0.34) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12787028 0.82 RAD1 (0.53) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12724032 0.81 RAD1 (0.44) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12724043 0.80 RAD1 (0.46) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL18905227 0.79 SENP2 (0.52) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12846592 0.78 SENP2 (0.51) RAD1P2RY6SENP2SENP1SENP3
SCHEMBL12847588 0.78 SENP2 (0.42) RAD1P2RY6SENP2SENP1SENP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7931702-B2 Azo compound and salt thereof, and dye-containing polarizing film comprising the compound or salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-04-26 — — US disclosed
US-20090126127-A1 Azo compound and salt thereof, and dye-containing polarizing film comprising the compound or salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090126127-A1 Azo compound and salt thereof, and dye-containing polarizing film comprising the compound or salt REN, RCC1, NR3C2 RAD1 3054/4885P2RY6 4767/4885SENP2 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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