Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1519979 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL12765770 | 0.85 | MAPT (0.60) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL664283 | 0.84 | MAPT (0.70) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL29053759 | 0.83 | MAPT (0.68) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL4092371 | 0.83 | ALDH1A1 (0.75) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| Indolylpropionic Acid SCHEMBL195405 | 0.82 | MAPT (0.68) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL28378507 | 0.82 | MAPT (0.68) | ALDH1A1MAPTGAAHPGDHTT | |
| Indolylpropionic Acid SCHEMBL29521227 | 0.82 | MAPT (0.68) | ALDH1A1MAPTGAAHPGDHTT | |
| Indolylpropionic Acid SCHEMBL29374161 | 0.82 | MAPT (0.68) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL2378991 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289083-A1 | IDO Inhibitors | NEWLINK GENETICS CORPORATION | 2013-10-31 | — | — | US | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | IDO1, IDO2, INMT | ALDH1A1 1077/4885MAPT 2968/4885GAA 911/4885 |
| US-20130289083-A1 | IDO Inhibitors | IDO1, IDO2, INMT | ALDH1A1 1238/4885MAPT 3083/4885GAA 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.