SCHEMBL1276707

SCHEMBL1276707

O=P(OF)(OF)Oc1ccccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
NOTUM Q6P988 1/20 0.37
ACP3 P15309 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36
IDO1 P14902 2/20 0.35
MAOB P27338 2/20 0.35
SLC22A12 Q96S37 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
FDFT1 P37268 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276704 0.82 PPARG (0.41) PPARGRXRARXRBRXRGLMNA
SCHEMBL31634474 0.81 KCNK3 (0.43) PPARGRXRARXRBRXRGLMNA
SCHEMBL25268384 0.81 INPPL1 (0.52) PPARGRXRARXRBRXRGLMNA
SCHEMBL30438792 0.78 ACP3 (0.41) PPARGRXRARXRBRXRGLMNA
SCHEMBL6475202 0.77 PPARG (0.40) PPARGRXRARXRBRXRGLMNA
SCHEMBL1009274 0.76 LMNA (0.47) LMNAGAAL3MBTL1HTT
SCHEMBL190944 0.72 TDP1 (0.45) RXRARXRBRXRGGAA
SCHEMBL29405225 0.72 TDP1 (0.45) RXRARXRBRXRGGAA
SCHEMBL1685381 0.72 LTA4H (0.46) PPARGRXRARXRBRXRGMRGPRX4
SCHEMBL1276884 0.72 LMNA (0.35) LMNAGAAL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330675-B1 SECONDARY BATTERY NEC CORP (JP) 2018-08-22 EP disclosed
US-20120171542-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2012-07-05 US disclosed
US-20110159379-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2011-06-30 US disclosed
EP-2330675-A1 SECONDARY BATTERY NEC Corporation (JP) 2011-06-08 EP disclosed
US-20110070504-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2011-03-24 US disclosed
EP-2280444-A1 SECONDARY BATTERY NEC Corporation (JP) 2011-02-02 EP disclosed
US-20080254361-A1 Non-Aqueous Electrolyte for Battery and Non-Aqueous Electrolyte Secondary Battery Comprising the Same BRIDGESTONE CORPORATION (JP) 2008-10-16 US disclosed