SCHEMBL6475202

SCHEMBL6475202

O=P(OOc1ccccc1C(F)(F)F)(OOc1ccccc1C(F)(F)F)OOc1ccccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
NOTUM Q6P988 1/20 0.37
ACP3 P15309 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
IDO1 P14902 2/20 0.35
SLC22A12 Q96S37 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
MAOB P27338 1/20 0.34
FDFT1 P37268 1/20 0.33
LTA4H P09960 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276707 0.77 PPARG (0.40) PPARGRXRARXRBRXRGLMNA
SCHEMBL1276704 0.74 PPARG (0.41) PPARGRXRARXRBRXRGLMNA
SCHEMBL15631713 0.74 PPARG (0.42) PPARGRXRARXRBRXRGLMNA
SCHEMBL6474607 0.74 LMNA (0.41) PPARGLMNAGAAL3MBTL1
SCHEMBL25268384 0.73 INPPL1 (0.52) PPARGRXRARXRBRXRGLMNA
SCHEMBL11387279 0.72 PPARG (0.41) PPARGRXRARXRBRXRGMRGPRX4
SCHEMBL3488959 0.72 ADRA2A (0.39) PPARGRXRARXRBRXRGLMNA
SCHEMBL1685381 0.72 LTA4H (0.46) PPARGRXRARXRBRXRGMRGPRX4
SCHEMBL31634474 0.70 KCNK3 (0.43) PPARGRXRARXRBRXRGLMNA
SCHEMBL1577430 0.70 PPARG (0.44) PPARGRXRARXRBRXRGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846542-B1 UV treatment for improving performance of lubricated thin film recording media and media obtained thereby SEAGATE TECHNOLOGY LLC (US) 2005-01-25 US claimed
US-6846542-B1 UV treatment for improving performance of lubricated thin film recording media and media obtained thereby SEAGATE TECHNOLOGY LLC (US) 2005-01-25 US disclosed