Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774909 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL14897890 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL12725220 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL14723025 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL1277126 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL120619 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL14816400 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL15969661 | 0.99 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL15509553 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAACES1CDC25A | |
| SCHEMBL31248093 | 0.92 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAACES1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773687-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | Corning Inc. (US) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013066973-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2013-05-10 | — | — | WO | disclosed |
| US-20130085256-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED | 2013-04-04 | — | — | US | disclosed |
| US-20120085992-A1 | Furan Conjugated Polymers Useful for Photovoltaic Applications | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085256-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TPR | ALDH1A1 3322/4885KDM4E 854/4885GAA 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.